Sulphur Linkages in Proteins

Clostridial iron-sulphur proteins.

Iron-sulfur proteins are ubiquitous catalysts of a wide range of biological reactions, and are particularly abundant in clostridia which lack the ability to synthesize hemes. The development of research on these metalloproteins has therefore been strongly associated with biochemical investigations of clostridial metabolism. Major breakthroughs in the field, from the first isolation of an iron-s...

Iron Sulphur Proteins, Volume 3

On the positive side, the concept of this series seeks to fill a genuine gap in the present literature with clear, straightforward, detailed and up-to-date accounts of the theory behind the many separation techniques currently available to biochemists. The extent to which it succeeds depends, not only on the quality of the individual contributors, but also on skilful editing. Catsimpoolas can b...

Clxxiv. the Sulphur Distribution of Proteins

Biological functions of iron-sulphur proteins.

Annotating proteins with generalized functional linkages.

As genome sequencing outstrips the rate of high-quality, low-throughput biochemical and genetic experimentation, accurate annotation of protein function becomes a bottleneck in the progress of the biomolecular sciences. Most gene products are now annotated by homology, in which an experimentally determined function is applied to a similar sequence. This procedure becomes error-prone between mor...